Portfolio

Top 10 Holdings as of 9/30/2021

Moderna, Inc. 10.1%
Gilead Sciences, Inc. 6.8%
Amgen, Inc. 6.1%
Regeneron Pharmaceuticals, Inc. 4.9%
Horizon Therapeutics plc 4.6%
Illumina, Inc. 3.9%
Biogen, Inc. 3.5%
Vertex Pharmaceuticals, Inc. 3.3%
Seagen, Inc. 3.0%
Alnylam Pharmaceuticals, Inc. 2.4%

This data is subject to change on a daily basis. Percentage of net assets.

Sub-Sector Allocation as of 9/30/2021

Biotechnology 73.6%
Pharmaceuticals 14.0%
Life Sciences Tools & Services 5.1%
Health Care Equipment & Supplies _x000D_ 3.5%
Money Market Fund 1.7%
Repurchase Agreement 1.6%
Healthcare Services 1.4%
Health Care Providers & Services 0.8%
Special Purpose Acquisition Company 0.1%
Other Liabilities in Excess of Assets -1.8%

This data is subject to change on a daily basis.

Asset Allocation as of 9/30/2021

Common Stocks 92.0%
Convertible Preferred 4.8%
Short-term Investments 3.3%
Milestone Interests 1.3%
Put Option Contracts Purchased 0.6%
Call Option Contracts Written -0.2%
Other Liabilities In Excess Of Assets -1.8%

This data is subject to change on a daily basis. Percentage of net assets.