Portfolio

Top 10 Holdings as of 9/30/2018

Biogen Inc. 8.10%
Gilead Sciences, Inc. 7.30%
Amgen Inc. 6.90%
Celgene Corporation 6.30%
Illumina, Inc. 5.80%
Vertex Pharmaceuticals Incorporated 4.90%
Regeneron Pharmaceuticals, Inc. 3.90%
Alexion Pharmaceuticals, Inc. 3.40%
Incyte Corporation 2.60%
Mylan N.V. 2.30%

This data is subject to change on a daily basis. Percentage of net assets.

Sub-Sector Allocation as of 9/30/2018

Biotechnology 72.5%
Pharmaceuticals 12.0%
Life Sciences Tools & Services 7.2%
Health Care Equipment & Supplies _x000D_ 3.3%
Repurchase Agreement 2.7%
Medical Devices and Diagnostics 0.2%
Drug Discovery Technologies 0.1%
Health Care Providers & Services 0.1%
Other Assets in Excess of Liabilities 1.9%

This data is subject to change on a daily basis.

Asset Allocation as of 9/30/2018

Common Stocks And Warrants 89.7%
Convertible Preferred And Warrants 3.6%
Short-Term Investment 2.7%
Milestone Interests 1.8%
Convertible Notes 0.3%
Other Assets In Excess Of Liabilities 1.9%

This data is subject to change on a daily basis. Percentage of net assets.